Cefpodoxime (Vantin): A Complete Guide

Cefpodoxime is a prescription antibiotic used to treat a variety of bacterial infections. It belongs to the cephalosporin class of antibiotics and works by preventing bacteria from growing. Note that Cefpodoxime is not effective against viral infections such as the common cold or flu. Misuse or unnecessary use of antibiotics can lead to decreased effectiveness.

Uses of Cefpodoxime

Cefpodoxime treats various bacterial infections. It is particularly effective in stopping bacteria from growing, thus helping the body fight the infection.

NoteThis antibiotic is for bacterial infections only and will not work for viral infections.

How to Use Cefpodoxime Proxetil

  • Take orally as directed by your doctor, typically every 12 hours.
  • For tablets, take with food to enhance absorption.
  • For suspension, it can be taken with or without food. Shake the bottle well before each dose.
  • Based on medical condition and response. For children, dosage is weight-based.
  • PPIs and antacids can decrease the absorption. Take antacids at least 2 hours before or after cefpodoxime.
  • Take at evenly spaced intervals for the best effect.
  • Continue the full prescribed course, even if symptoms disappear.

Side Effects of Cefpodoxime

Common Side Effects:

  • Abdominal pain
  • Diarrhea
  • Headache
  • Nausea
  • Rash

Serious Side Effects:

  • Severe dizziness or fainting
  • Confusion or weakness
  • Unusual bleeding or bruising
  • Yellowing of the skin or eyes (jaundice)
  • Watery or bloody diarrhea

Note:Contact your doctor if you experience any serious side effects.

Precautions While Taking Cefpodoxime Injection

  • Allergies: Inform your doctor if you are allergic to cefpodoxime, penicillins or other cephalosporins.
  • Medical History: Disclose any history of kidney disease or gastrointestinal diseases (e.g., colitis) to your doctor.
  • Vaccinations: Live bacterial vaccines may not work as well. Avoid immunizations/vaccinations unless advised by your doctor.

Cefpodoxime Dosage

Pediatric and Adult Dosages:

  • Suspension (Oral): 50 mg/5 ml, 100 mg/5 ml
  • Tablet: 100 mg, 200 mg

Antipsychotic drugs, lorcaserin, metoclopramide, and certain antifungal agents can affect how cefpodoxime works. Ensure to discuss all medications you’re taking with your doctor to avoid interactions.

Missed Dose and Overdose

  • Missed Dose: Take as soon as you remember unless it’s close to your next dose. Do not double the dose.
  • Overdose: Seek immediate medical attention. Symptoms may include extreme dizziness, hallucinations, or fainting.

Storage

  • Store at room temperature away from sunlight, heat, and moisture.
  • Do not store it in the bathroom.
  • Properly dispose of expired or unused medication. Consult your pharmacist for disposal instructions.

Cefpodoxime vs Amoxicillin

Cefpodoxime Amoxicillin
Formula: C21H27N5O9S2 Formula: C16H19N3O5S
Oral antibiotic Amoxicillin is an antibiotic
Molar mass: 427.458 g/mol Molecular Weight: 365.4 g/mol
This antibiotic only treats bacterial infections. used for treating the number of bacterial infections such as middle ear infections, throat, pneumonia, skin infections, and urinary tract infections
This antibiotic only treats bacterial infections. used for treating the number of bacterial infections such as middle ear infections, throat, pneumonia, skin infections, and urinary tract infections
Administered orally Given orally or by injection
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