Prostin, also known as Dinoprostone, is a prostaglandin E2 (PGE2) that occurs naturally in the body. It is used medically to induce labor, aid in cervical ripening, and manage certain pregnancy-related conditions.
Prostin Uses:
Labor Induction: Used to prepare the cervix for labor induction near term (end of pregnancy).
Abortion: Can be used to induce abortion between 12 to 20 weeks of pregnancy, or to manage incomplete abortion or miscarriage up to 28 weeks of pregnancy.
Other Uses: Also used for treating benign hydatidiform mole, a specific type of uterine condition.
Prostin Side Effects:
Common Side Effects: Fever, irregular heartbeats, nausea, stomach pain, and back pain.
Serious Side Effects: Light-headed feeling, weak or shallow breathing, vaginal bleeding, unexpected stomach pain, chest pain, easy bruising, and bleeding from wounds.
Precautions:
Allergies: Inform your doctor of any allergies to Prostin or related medications.
Medical History: Discuss any history of anemia, asthma, low blood pressure, diabetes, glaucoma, heart disease, kidney disease, liver disease, infections in the vaginal area, or seizure disorder.
How to Take Prostin:
Administration: Inserted vaginally as a suppository by a healthcare provider.
Positioning: Remain reclined or lying down for at least 10 minutes after insertion.
Dosage: Additional doses may be given every 3-5 hours until the desired effect (contractions or abortion) is achieved, typically not exceeding 48 hours.
Hospital Setting: It should only be used in a hospital under medical supervision due to the need for monitoring and potential complications.
Storage:
Store at room temperature (68ºF to 77ºF), away from heat, light, and moisture. Keep out of reach of children.
Prostin vs Cytotec (Misoprostol):
Prostin (Dinoprostone): Naturally occurring prostaglandin used for labor induction and managing specific uterine conditions.
Cytotec (Misoprostol): Used primarily to prevent stomach ulcers when taking nonsteroidal anti-inflammatory drugs (NSAIDs) and for inducing abortion or managing postpartum hemorrhage.
Side Effects Comparison:
Prostin: Fever, irregular heartbeats, nausea, stomach pain, back pain.