Seroquel (quetiapine) is an atypical antipsychotic drug used to treat several psychiatric and mood disorders, including schizophrenia, bipolar disorder, and severe depression. It helps restore the brain’s chemical balance, managing symptoms and improving quality of life.
Brand Names: Seroquel, among others
Uses: Treatment of schizophrenia, bipolar disorder, and major depressive disorder
Seroquel Uses
Seroquel is prescribed for:
Schizophrenia in adults and adolescents aged 13 and up
Bipolar disorder, including manic episodes and depression associated with bipolar disorder
Major depressive disorder as an adjunct treatment
This medication helps:
Reduce hallucinations
Improve concentration and mood
Decrease anxiety
Stabilize mood swings
Enhance sleep, appetite, and energy levels
How to Take Seroquel
Administration: Oral, with or without food
Frequency: 2 or 3 times daily; for bipolar depression, usually once a day at bedtime
Dosage: Determined by medical condition, response to treatment, and other medications being taken
Note: Start with a low dose and gradually increase as directed by your doctor
Important Guidelines
Consistency: Take the medication regularly to gain the most benefit.
Adjustment: Do not increase dosage or take more frequently than prescribed.
Continuation: Even if feeling well, do not stop the medication abruptly. Consult your doctor first.
Withdrawal: Gradual reduction may be necessary to avoid withdrawal symptoms (e.g., sleep issues, nausea, irritability).
Side Effects
Common side effects include:
Mood or behavior changes
Constipation
Stomach pain, upset stomach, nausea, vomiting
Drowsiness, dizziness, lightheadedness, tiredness
Headache
Trouble sleeping
Dry mouth, sore throat
Breast swelling or discharge missed menstrual periods
Increased appetite, weight gain
Precautions
Before taking Seroquel, inform your doctor if you have:
Allergies to quetiapine or other medications
Eye conditions (e.g., cataracts)
Liver disease
Low white blood cell count
Difficulty swallowing
Seizure disorders
Thyroid issues
Gastrointestinal blockages
Special Considerations
Dizziness/Drowsiness: Avoid alcohol and cannabis. Do not drive or operate machinery until you are certain of the drug’s effects.
QT Prolongation: Seroquel may cause heart rhythm problems. Monitor heart health and report any irregularities.
Children: Increased risk of blood pressure elevation and increased prolactin levels.
Elderly: Increased risk of severe side effects such as drowsiness and dizziness.
Pregnancy and Breastfeeding
Pregnancy: Use only if needed. Monitor newborns for symptoms if taken during the last three months of pregnancy.
Breastfeeding: The drug may pass into breast milk. Consult your doctor before breastfeeding.
Drug Interactions
Seroquel can interact with various medications, including: