Sertraline: Uses, Side Effects, Dosage and Precautions

Sertraline is an antidepressant belonging to the selective serotonin reuptake inhibitors (SSRIs) class. It helps regulate brain chemicals associated with depression, anxiety, and obsessive-compulsive symptoms. Sold under the brand name Zoloft, sertraline offers a higher degree of tolerability compared to other antidepressants known for causing excessive drowsiness and other adverse effects.

Sertraline Uses

  • Treats depression, anxiety disorders, and various mood disorders.
  • Used for obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder (PTSD) and premenstrual dysphoric disorder (PMDD) to alleviate symptoms like bloating, mood swings, and irritability.

Sertraline Side Effects:

  • Common: Nausea, diarrhea, constipation, vomiting, dry mouth, heartburn, loss of appetite, dizziness, nervousness.
  • Serious: Seizures, abnormal bleeding, agitation, hallucinations, weakness, rash, hives.

Precautions

  • Discuss allergies to sertraline or other medications with your doctor.
  • Inform your doctor of medical history including bipolar disorder, bleeding problems, liver disease, seizure disorder, thyroid disease, and glaucoma.
  • Sertraline may cause QT prolongation leading to serious irregular heartbeats.
  • Take precautions if using during pregnancy or breastfeeding.

How to Take Sertraline

  • Available in oral tablet and liquid concentrate forms.
  • Take once daily, either morning or evening, with or without food.
  • Dilute the concentrate as directed before use.

Dosage of Sertraline

  • Major Depressive Disorder: 50 mg/day.
  • Obsessive-Compulsive Disorder: 50 mg/day.
  • Panic Disorder: 25 mg/day.

Missed Dose and Overdose:

  • Take missed doses as soon as remembered; do not double doses.
  • Overdose can lead to harmful effects, seek medical help if overdose occurs.

Warnings for Serious Health Conditions:

  • Considerations for kidney problems, bipolar disorder, and seizures.

Storage:

  • Store at room temperature (68ºF to 77ºF) away from heat, light, and moisture.

For further details and personalized advice, consult your healthcare provider.

Sertraline vs Fluoxetine

Sertraline Fluoxetine
Sertraline affects brain chemicals that may be out of whack in people suffering from depression, fear, anxiety, or obsessive-compulsive symptoms. Fluoxetin is a selective serotonin reuptake inhibitor antidepressant. The medication inhibits the uptake of serotonin by nerve cells
People use Sertraline tablets for treating depression, anxiety and various mood disorders. Ondansetron tablets are used for preventing nausea and vomiting caused due to some medical treatment.
Some of the common side effects of Sertraline are:

  • Nausea
  • Diarrhea
  • Constipation
  • Vomiting
Some of the common side effects of Fluoxetin are:

  • Nervousness
  • Anxiety
  • Difficulty in falling asleep
  • Nausea
  • Diarrhea
  • Dry mouth
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