Digoxin, sold under the brand name Lanoxin, is a medication used to treat various heart conditions such as atrial fibrillation, atrial flutter, and heart failure. It can be taken orally or by injection into a vein.
Uses of Digoxin
Treats heart failure, usually in combination with other medications.
Treats certain types of irregular heartbeat, such as chronic atrial fibrillation.
Helps improve the strength of the heart, maintain the ability to walk and exercise, and stabilize heart rhythm.
How Digoxin Works
Digoxin belongs to the class of medications known as cardiac glycosides. It works by affecting the balance of sodium and potassium in heart cells, which helps reduce the strain on the heart and maintain a normal, steady, and strong heartbeat.
How to Use Digoxin
Take orally with or without food, usually once a day as directed by your doctor.
For the liquid form, use the provided dropper for accurate dosing; do not use a household spoon.
Take at least 2 hours before or after consuming high-fiber foods or certain medications like cholestyramine, colestipol, or psyllium.
If taking antacids, kaolin-pectin, milk of magnesia, metoclopramide, sulfasalazine, or aminosalicylic acid, space them as far apart from your digoxin dose as possible.
Dosage is based on medical condition, age, body weight, lab tests, and response to treatment.
Use regularly at the same time every day to maximize benefits and avoid sudden discontinuation without consulting your doctor.
Side Effects of Digoxin
Common side effects include:
Dizziness
Mental disturbances
Diarrhea
Headache
Nausea
Vomiting
Redness of skin
Bumpy rash
Loss of appetite
Irregular heartbeat
Visual disturbances (e.g., yellow vision)
Serious side effects include:
Heart block
Cardiac arrest rhythm (asystole)
Fast heart rate
Arrhythmia in children
Precautions
Inform your doctor if allergic to digoxin, digitoxin, or any other substances.
Discuss your medical history, especially regarding kidney problems or thyroid issues.
Avoid activities requiring alertness or clear vision if experiencing dizziness or blurred vision.
Be cautious with alcohol or marijuana, as they can increase dizziness.
Maintain a balance of natural minerals (calcium, magnesium, potassium) as imbalances can affect digoxin’s efficacy.
Inform your healthcare provider about all the drugs you are taking, especially diuretics.
Use during pregnancy only if clearly needed; consult your doctor.
Interactions
Interactions may alter how your medications work or increase side effects.
Inform your doctor about all medicines you use, including over-the-counter drugs and supplements.
Be cautious with products that may worsen heart failure, such as NSAIDs.
Monitoring
Regular blood tests (e.g., digoxin levels, blood mineral levels), kidney function tests, and electrocardiograms are necessary.
Keep all medical and laboratory appointments.
Learn to check your blood pressure and pulse at home and share results with your doctor.
Missed Dose
Take the missed dose within 12 hours of the scheduled time. If more than 12 hours have passed, skip the missed dose and resume the regular schedule. Do not double the dose to catch up.
Overdose
Symptoms of overdose may include severe dizziness, fainting, trouble breathing, and abnormal heart rhythms. Seek emergency medical attention or contact a poison control center immediately.
Storage
Store at room temperature, away from moisture and heat.
Protect from sunlight and humidity; do not store in the bathroom.
Keep all medications out of reach of children and pets.
Properly dispose of expired or no longer needed medications as per local regulations or consult your pharmacist.
Comparison: Digoxin vs. Metoprolol
Attribute
Digoxin
Metoprolol
Brand Name
Lanoxin
Lopressor
Formula
C41H64O14
C15H25NO3
Primary Use
Treats heart failure, chronic atrial fibrillation
Treats high blood pressure, chest pain, and fast heart conditions
Medication Class
Cardiac glycoside
Beta-blocker
Administration
Can be taken with or without food
Should be taken before meals or at bedtime
For any further information, always consult your healthcare provider or pharmacist.
